(±)-α-Lipoic Acid

(±)-α-Lipoic acid, also known as thioctic acid, is a naturally occurring organosulfur compound derived from octanoic acid. It serves as a coenzyme in mitochondrial energy metabolism and functions as a potent antioxidant, capable of neutralizing free radicals and regenerating other antioxidants like glutathione, vitamin C, and vitamin E. Due to its fat- and water-soluble properties, α-lipoic acid can work in various biological environments, making it highly effective in metabolic and neuroprotective applications.

Applications of (±)-α-Lipoic Acid

1. Pharmaceutical and Nutraceutical Uses

• Supports mitochondrial function by participating in enzymatic energy production.
• Additionally, it reduces oxidative stress and improves cellular defense mechanisms.
• Commonly used in dietary supplements for neuropathy, diabetes, and anti-aging benefits.
• Moreover, it enhances insulin sensitivity, making it valuable in diabetes management.

2. Antioxidant and Anti-Inflammatory Applications

• Neutralizes free radicals, reducing oxidative damage to cells and tissues.
• Furthermore, it recycles and enhances the effectiveness of glutathione, vitamin C, and vitamin E.
• Additionally, it reduces inflammation, benefiting conditions such as neurodegenerative diseases and cardiovascular health.

3. Cosmetic and Dermatological Formulations

• Incorporated in anti-aging creams and serums due to its ability to reduce wrinkles and fine lines.
• Moreover, it protects skin against UV radiation and environmental stressors.
• Additionally, it enhances skin elasticity by supporting collagen production.

4. Industrial and Research Applications

• Used as a biochemical reagent in research studies related to metabolism and cellular signaling.
• Furthermore, it is investigated for its potential in heavy metal detoxification due to its ability to chelate harmful metals.
• Additionally, it is studied for its neuroprotective effects in conditions like Alzheimer’s and Parkinson’s disease.

Features and Benefits

• Powerful Antioxidant: Effectively neutralizes free radicals and supports antioxidant regeneration
• Metabolic Support: Plays a crucial role in mitochondrial energy production
• Dual Solubility: Functions in both lipid and aqueous environments for versatile activity
• Neuroprotective Effects: May aid in reducing nerve damage and improving cognitive function
• Skin and Cellular Health: Protects against oxidative stress and enhances collagen stability

Safety and Handling

• Store in a cool, dry place, away from heat and direct sunlight
• Use protective gloves and eyewear when handling in industrial or laboratory settings
• Follow proper disposal procedures for laboratory and pharmaceutical applications
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